Correlation between p53 expression and clinical-pathological characteristics of gastric cancer

[Correlation between p53 expression and clinical-pathological characteristics of gastric cancer].

UNLABELLED BACKGRAUND/AIM: Gene p53, or "cell genome keeper", has a preventive effect on the occurrence of genetic aberrations and prevents abnormal expansion of (tumor) cells. In gastric cancer cells in most cases we register high expression of mutated p53 gene, which correlates with prognosis and specific clinical-pathological characteristics of gastric cancer. METHODS Using the imunohistoc...

Correlation of ER, PR, HER- 2 and P53 Immunoreactions with Clinico-Pathological Features in Breast Cancer

  Background and Objectives: The most prevalent malignancy among women is known to be breast cancer (BC). Several factors contribute to determining tumor prognosis and treatment strategies. In this study, the frequency and relevance of these factors are discussed. Materials and Methods: This cross-sectional study was carried out on 214 patients with BC, who referred to the Cancer Institute of...

Ki-67 Expression in Gastric Cancer and Correlation with Clinico-Pathological Characteristics

Background: The characteristics of the cellular kinetic reflect the aggressiveness of the tumors and even their prognosis, many studies proving the correlation between the increased proliferation activity and a poor prognosis in a variety of neoplasms. Aim: The analysis of immunohistochemical Ki-67 expression in 55 patients with gastric cancer, the correlation with clinico-pathological factors ...

Relationship between demographic and pathological characteristics on the 5-year survival rate of gastric cancer patients in Tehran province

MECP2 expression in gastric cancer and its correlation with clinical pathological parameters

This study is to investigate the expression of methyl CpG binding protein 2 (MECP2) in gastric cancer (GC) and its clinical significance.Expression of MECP2 was analyzed in 69 cases of GC tissues and 12 paracancerous tissues, either by qRT-PCR at the mRNA level or by Western blot and immunochemistry at the protein level. The correlation of MECP2 expression with clinicopathological parameters wa...